Michael Appleton’s side will be looking to get back to winning way after slumping to a 1-0 defeat to Blackburn Rovers in midweek.
They will of course be without Josh Bowler, who departed on deadline day, but new signing Callum Wright is available to feature after sealing a permanent move from Leicester City.
The Seasiders are still without seven first-team players through a combination of injuries and suspension, although the problems are finally beginning to ease.
But how they will line-up at the John Smith’s Stadium? Here’s our prediction?
The Seasiders are still without seven first-team players through a combination of injuries and suspension, although the problems are finally beginning to ease.
. Looking for a reaction
The Seasiders will be looking to get back to winning ways after Wednesday night's disappointment Photo: CameraSport - Alex Dodd
. GK - Dan Grimshaw
Grimmy produced some stunning saves even in defeat on Wednesday night. Photo: CameraSport - Dave Howarth
. RB - Jordan Gabriel
Gabriel will want to banish his bad memories of being sent off at Huddersfield last season. Photo: CameraSport - Dave Howarth
7. CM - Kenny Dougall
The Aussie will be keen to issue a response after a poor display in midweek. Photo: CameraSport - Dave Howarth
8. CM - Callum Connolly
Both Connolly and Dougall could do with an extra man in midfield to stop Blackpool from being overrun. Photo: CameraSport - Dave Howarth
9. CM - Callum Wright
We know Appleton is desperate to return to 4-3-3, so I can see the debutant being thrown straight in from the start. Photo: Blackpool FC
10. RW - Ian Poveda
Poveda might be the man tasked with replacing Bowler, although Appleton recently revealed the loanee might only be able to start for 60 minutes. Photo: CameraSport - Lee Parker
11. LW - Theo Corbeanu
Corbeanu may be handed a start in place of Shayne Lavery, who has been below-par during the last few outings. Photo: CameraSport - Dave Howarth
12. ST - Jerry Yates
If picked to start, Jerry will be looking for a repeat of the clinical finish he produced at the John Smith's Stadium last season. Photo: CameraSport - Dave Howarth