The fixture holds importance for several reasons, including what it could mean for the Seasiders’ League One status beyond this season - along with the six matches beyond that.
Ian Evatt’s side currently sit 21st in the third tier, and will be hoping to use their recent 3-2 victory over Port Vale and 0-0 stalemate away to Cardiff City as a platform to build a survival charge on.
Burton are currently four points above Blackpool, with this weekend’s game having the potential to either drag them back into the mix or give them a massive boost in their own hopes of surviving the drop.
Both Bailey Peacock-Farrell and Karoy Anderson are unavailable for this weekend, with the pair on international duty with Northern Ireland and Jamaica respectively.
Here’s our predicted XI and bench to take on the Brewers:
1. Franco Ravizzoli
With Bailey Peacock-Farrell away, Franco Ravizzoli will get an opportunity in goal. Photo: Gareth Evans
2. Reuell Walters
A deflection off Reuell Walters gave Blackpool a winner against Port Vale in their last home game. Photo: Gareth Evans
3. Fraser Horsfall
Fraser Horsfall was among those to produce a solid defensive display away to Cardiff last weekend. Photo: Gareth Evans
4. Olly Casey
Olly Casey also enjoyed a strong afternoon in South Wales. Photo: Gareth Evans
5. James Husband
James Husband produced a crucial block to deny Cardiff a clear goal scoring opportunity last weekend. Photo: Gareth Evans
6. Josh Bowler
Josh Bowler was a shining light in Blackpool's last home game. Photo: Gareth Evans