The fixture holds importance for several reasons, including what it could mean for the Seasiders’ League One status beyond this season - along with the six matches beyond that.
Ian Evatt’s side currently sit 21st in the third tier, and will be hoping to use their recent 3-2 victory over Port Vale and 0-0 stalemate away to Cardiff City as a platform to build a survival charge on.
Burton are currently four points above Blackpool, with this weekend’s game having the potential to either drag them back into the mix or give them a massive boost in their own hopes of surviving the drop.
Both Bailey Peacock-Farrell and Karoy Anderson are unavailable for this weekend, with the pair on international duty with Northern Ireland and Jamaica respectively.
Here’s our predicted XI and bench to take on the Brewers:
7. Jordan Brown
Jordan Brown has been among those to vastly improve in the last two games. Photo: Gareth Evans
8. George Honeyman
George Honeyman could return to the starting XI with Karoy Anderson on international duty. Photo: Gareth Evans
9. CJ Hamilton
CJ Hamilton offered some important defensive contributions away to Cardiff. Photo: Gareth Evans
10. Ashley Fletcher
Ashley Fletcher has 21 goals under his belt so far this season in all competitions. Photo: Gareth Evans
11. Niall Ennis
Niall Ennis was on target against Port Vale and could return to the starting XI for his natural goal scoring touch. Photo: Gareth Evans
12. SUB: Harvey Bardsley
Harvey Bardsley could be Blackpool's back-up goalkeeper this weekend. Photo: Gareth Evans