Ian Evatt’s side will be looking to set the tone early on, and head into their League One opener against Wycombe Wanderers with a spring in their step from Blundell Park.
Having missed the majority of pre-season action, Albie Morgan, George Honeyman and Leighton Clarkson should all be back to boost the club’s midfield options.
It remains 50/50 whether Tom Bloxham will be back in time, but Fraser Horsfall, Michael Ihiekwe and Dion Charles are all confirmed out.
Here’s our predicted XI and bench to take on Grimsby:
7. Karoy Anderson
Karoy Anderson's return on a permanent deal has been welcomed by all at Bloomfield Road. Photo: Gareth Evans
8. Hayden Coulson
With other players working their way back to fitness after minor injuries, Hayden Coulson could be used in the midfield three. Photo: Gareth Evans
9. Ilmari Niskanen
Ilmari Niskanen has showcased snippets of what he's about following his move from Exeter. Photo: Gareth Evans
10. Dale Taylor
Dale Taylor will be looking to put his injury-hit first season in Tangerine behind him. Photo: Gareth Evans
11. Niall Ennis
Niall Ennis will also be hoping to stay off the treatment table after various disruptions during his first full year at Bloomfield Road. Photo: Gareth Evans
12. SUB: Franco Ravizzoli
Franco Ravizzoli has mainly been used as a back-up goalkeeper during his time at Bloomfield Road. Photo: Gareth Evans