TEAM NEWS: Pool make three changes for Wigan clash
Kyle Vassell isn't included in the squad, meaning Armand Gnanduillet takes his place in attack.
Jimmy Ryan also returns to the side in place of Jay Spearing, who drops to the bench.
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Hide AdColin Daniel also starts in midfield, as Callum Cooke misses out through injury.
Blackpool will be huge underdogs for tonight's game, having won just two of their last 18 games in a spell that has seen them drop to just two points above the League One dropzone.
Wigan, meanwhile, remain top of the league despite losing their 16-game unbeaten streak on Saturday in their 3-1 defeat at Southend United.
Wigan: Walton, Byrne, Dunkley, Burn, James, Morsy, Power, Massey, Jacobs, Powell, Grigg
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Hide AdSubs: Jones, Perkins, Walker, Vaughan, Bruce, Roberts, Fulton
Blackpool: Lumley, Mellor, Tilt, Robertson, Turton, Ryan, Longstaff, Solomon-Otabor, Daniel, Delfouneso, Gnanduillet
Subs: Mafoumbi, Taylor, Aimson, Spearing, D'Almeida, Philliskirk, Agyei
Referee: Rob Jones