They will do so without as many as 10 players, with nine out injured and Gary Madine serving the second match of his four-game suspension.
There is better news regarding Curtis Nelson though, with the defender returning to training after missing the weekend draw with Rotherham with a groin strain.
With that in mind, here’s how we think the Seasiders might line up against Russell Martin’s side...
With that in mind, here’s how we think the Seasiders might line up against Russell Martin’s side...
7. CM - Kenny Dougall
The Seasiders will certainly need Dougall's defensive nous given they're now without the services of Tom Trybull. Photo: CameraSport - Dave Howarth
8. CM - Charlie Patino
The Arsenal loanee is likely to start having replaced the injured Tom Trybull early into Saturday's game. Photo: CameraSport - Dave Howarth
9. CM - Sonny Carey
The Seasiders need Carey to be at his best with his driving runs from midfield, especially on the transition. Photo: CameraSport - Dave Howarth
10. RW - Josh Bowler
After Saturday's battle against Rotherham, this could be a game that is better suited to Bowler with gaps likely to appear in the wide areas. Photo: CameraSport - Dave Howarth
11. LW - CJ Hamilton
While Morgan Rogers is certainly in the frame for a start, Hamilton's pace could be a huge asset in behind. Photo: CameraSport - Dave Howarth
12. ST - Jerry Yates
Pool need to get Yates firing again if they're to stay up this season. They also need to keep him fit given he's the only available striker at this minute. Photo: CameraSport - Dave Howarth