The 64-year-old confirmed Keshi Anderson is in contention to make his squad while both Lewis Fiorini and Ian Poveda are also available after a line was drawn under their recent disciplinary issue.
Gary Madine, however, is to miss out as a result of the knee injury he suffered against Bristol City on Saturday.
Speaking ahead of Tuesday night’s game, McCarthy hinted there would be at least a “couple” of changes to his side.
1. Improvements needed
The Seasiders will need to be much improved from their drab display at Ashton Gate on Saturday Photo: CameraSport - Ian Cook
2. GK - Chris Maxwell
Maxwell could do little about Bristol City's goals on Saturday. Despite not wearing the armband, he's still one of the main leaders inside the dressing room. Photo: CameraSport - Ian Cook
3. RB - Jordan Gabriel
Andy Lyons will be pushing to get back in the side, but Gabriel did okay on Saturday and looks pretty fresh. Photo: CameraSport - Ian Cook
4. CB - Curtis Nelson
The centre-back was Blackpool's standout performer at Ashton Gate on Saturday. Photo: CameraSport - Dave Howarth
5. LB - Jordan Thorniley
Thorniley was close behind Curtis Nelson for Saturday's Man of the Match following another consistent display. Photo: CameraSport - Ian Cook
6. LB - James Husband
Hubby would provide plenty of experience and know-how in place of Dom Thompson, who didn't have his best game at the weekend. Photo: CameraSport - Dave Howarth