A number of clubs have made emphatic starts to the new campaign, while overs will be looking for an upturn in form throughout the next few months.
There’s still plenty to play for, but some sides are already clear favourites to go up to the Championship.
Here are the latest League One promotion odds according to Sky Bet:
1. Who are the favourites to go up?
Where do Blackpool rank in the bookies' favourites for League One promotion? Photo: CameraSport - Lee Parker
2. Shrewsbury- 250/1
Shrewsbury currently sit 18th in the league after 11 games. Photo: Richard Heathcote
3. Carlisle United- 150/1
Carlisle United were promoted to League One last year via the play-offs. Photo: Paul Harding
4. Burton Albion- 150/1
Burton have only won two games in League One so far this season. Photo: Clive Mason
5. Reading- 80/1
Reading have had their fair share of problems off the field this season. Photo: Bryn Lennon
6. Fleetwood Town- 80/1
Lee Johnson has recently taken over as Fleetwood manager. Photo: Mark Runnacles