Neil Critchley’s side will be aiming to finish on a high after an excellent first year back in the Championship.
But how have they fared on the final day in recent years? We take a look back...
1. 2020/21 - Win
With a play-off spot already assured, the Seasiders beat Bristol Rovers 1-0 to finish in third place.
Photo: Martin Rickett
2. 2019/20 - No game
Blackpool didn't have a final game of the season as the campaign was curtailed early due to Covid. Their final game ended in a 2-1 defeat to Tranmere Rovers.
Photo: CameraSport - Alex Dodd
3. 2018/19 - Defeat
Tom Eaves scored twice as the Seasiders lost 3-0 at home to Gillingham.
Photo: CameraSport - Kevin Barnes
4. 2017/18 - Defeat
A solid first season back in League One ended with a 1-0 defeat to Rotherham United.
Photo: JPI Media