Bizarrely, it’s the first of three straight games against the sides that have already been relegated to League One.
Here’s how we think the Seasiders might line up...

. Blackpool's Gary Madine celebrates scoring his side's first goal with his team mates Photographer Andrew Kearns/CameraSport The EFL Sky Bet Championship - Luton Town v Blackpool - Saturday 23rd April 2022 - Kenilworth Road - Luton World Copyright © 2022 CameraSport. All rights reserved. 43 Linden Ave. Countesthorpe. Leicester. England. LE8 5PG - Tel: +44 (0) 116 277 4147 - [email protected] - www.camerasport.com
Will Neil Critchley keep faith with Gary Madine and Jake Beesley in attack? Photo: CameraSport - Andrew Kearns

. GK - Chris Maxwell
Dan Grimshaw has only just returned to intensive full team training. Photo: CameraSport - Dave Howarth

. RB - Callum Connolly
Connolly will be required at right-back again with Jordan Gabriel and Dujon Sterling still out. Photo: CameraSport - Dave Howarth

. CB - Marvin Ekpiteta
The centre-back has been one of the first names on the teamsheet all season long. Photo: CameraSport - Dave Howarth

7. CM - Matty Virtue
Now could be the perfect time to hand Virtue his first start of the season. Photo: CameraSport - Alex Dodd

8. RW - CJ Hamilton
Josh Bowler will be pushing to get back into the side, but CJ's pace could be a huge threat in behind. Photo: CameraSport - Rob Newell

9. LW - Keshi Anderson
Keshi has shown impressive discipline in central midfield, but he's better suited to a more creative role. Photo: CameraSport - Dave Howarth

10. ST - Shayne Lavery
It's unlikely Pool will require two big men in attack against Barnsley, so Lavery could come back in. Photo: CameraSport - Dave Howarth

11. ST - Jake Beesley
Madine or Beesley to start in attack? It's a toss of the coin. Beesley might just edge it for his mobility and movement. Photo: CameraSport - Dave Howarth