The Seasiders will know they will have to start picking up victories sooner rather than later if they want to have something to fight for come the latter end of the campaign.
After drawing their last four games, Steve Bruce’s side currently sit 15th in the League One table, and are 10 points off Stockport County – who currently occupy the final place in the play-offs.
A blow for Blackpool this weekend is the loss of Matthew Pennington, with the defender ruled out for the next four to six weeks with an ankle injury.
Here’s our predicted Seasiders XI and bench to take on Exeter:
1. Harry Tyrer
Harry Tyrer made an impressive save against Huddersfield Town to keep the game at 2-2 last weekend. Photo: CameraSport - Lee Parker
2. Odel Offiah
Odel Offiah's form has dipped in the last couple of games, but he's still enjoyed an impressive loan spell in Tangerine so far. Photo: CameraSport - Richard Martin-Rob
3. Elkan Baggott
The injury to Matthew Pennington should provide Elkan Baggott with a starting opportunity. Photo: CameraSport - Lee Parker
4. Olly Casey
Olly Casey has been a key figure for Blackpool this season. Photo: CameraSport - Richard Martin-Rob
5. James Husband
Last weekend's game marked James Husband's 200th appearance for Blackpool. Photo: CameraSport - Richard Martin-Rob
6. Rob Apter
Rob Apter claimed his fourth goal of the season in the Huddersfield game. Photo: CameraSport - Richard Martin-Rob