After a postponed kick off, with the game taking place an hour later than scheduled due to a heavy downpour at Prenton Park, the Seasiders edged their way in front after 18 minutes.
Scott Banks produced some quick foot work to avoid several challenges in the box, before releasing a shot past Jack Barrett.
Tranmere thought they had found an immediate equaliser, but Ravizzoli was just about able to stop the ball from crossing the line.
On their next attack, the home side were able to pull themselves level, with a shot from Brough taking a massive deflection to wrong foot Blackpool’s Argentine keeper.
After naming a number of Seasiders youngsters in his starting XI, Ian Evatt started to introduce further academy players off the bench in the second half.
It took the home side a bit of time to really make their mark against their junior opposition, before edging their way in front through a Joe Ironside header.
With qualification from Group B already confirmed for both teams ahead of kick off, the result only impacts their positioning, with Blackpool going through second.
Here’s how the Seasiders performed:

1. How did the Seasiders perform?
Blackpool took on Tranmere Rovers in the EFL Trophy at Prenton Park. Photo: Gareth Evans

2. Franco Ravizzoli - 6
There were a few shaky moments for Franco Ravizzoli, but was able to stop the majority of things that came his way. Photo: Gareth Evans

3. Andy Lyons - 7
Andy Lyons was able to slot back into the central defensive trio after dropping out at the weekend. Photo: Gareth Evans

4. Oluchukwu Nwankwo - 7
Oluchukwu Nwankwo started at the centre of the back three and would've learnt a lot from the experience in between two more senior players in the first half. Photo: Gareth Evans

5. Zac Ashworth - 7
Zac Ashworth put in a solid shift on the left side of the back three, and made some important blocks before being replaced at the break. Photo: Gareth Evans

6. Scott Banks - 7
Scott Banks was on hand with an impressive solo goal to open the scoring, with his quick feet taking him past a number of players. Photo: Gareth Evans