The Seasiders applied early pressure onto the visitors, with their first clear opening coming in the fifth minute.
A ball over the top from Reuell Walters found CJ Hamilton through in space, but the winger took a touch too many and couldn’t find a way past Jack Bycroft.
The next chance came moments after, with Ashley Fletcher seeing a shot vitally blocked in front of goal, before Joel Randall fired the rebound wide of the target from close-range.
It was a similar story for James Husband and Fraser Horsfall - who both placed a shots over the crossbar inside the box.
The deadlock was eventually broken ahead of the half hour mark, with Bloxham beating Bycroft to the ball just inside the area, before lifting a half volley over the Grecians keeper.
Exeter’s first real chance came just before break. An attempt from Jayden Wareham needed pushing over the bar by Bailey Peacock-Farrell - who reacted quickly after being untested for so long.
Following the restart, the Northern Ireland international made another important stop, blocking a flicked attempt from Jack Aitchison.
Ahead of the hour mark, there was a triple chance for Blackpool, with Hamilton having a shot saved, Jordan Brown having one blocked, and Hayden Coulson firing the third rebound just over.
Here’s how the Seasiders performed:
1. How did the Seasiders perform?
Blackpool took on Exeter City at Bloomfield Road. Photo: Gareth Evans
2. Bailey Peacock-Farrell - 8
Bailey Peacock-Farrell made a crucial save to keep Exeter out at the end of the first half. Photo: Gareth Evans
3. Reuell Walters - 8
Reuell Walters produced a good ball over the top to give CJ Hamilton an early opportunity, and did the same to assist Tom Bloxham for the opener. Beyond that, the fullback looked full of confidence bringing the ball forward. Photo: Gareth Evans
4. Fraser Horsfall - 8
Fraser Horsfall was among the players who couldn't find the target in the hunt for the opener, but was solid defensively. Photo: Gareth Evans
5. James Husband - 8
James Husband put an early chance over the bar from close-range, but like Horsfall looked comfortable in defence. Photo: Gareth Evans
6. Hayden Coulson - 7
Hayden Coulson did his job defensively and looked like a threat at times going forward. Photo: Gareth Evans