Scott Banks opened the scoring for the Seasiders after only six minutes, with the winger finishing on the rebound after an initial shot from Ashley Fletcher was saved.
After being denied by Ben Winterbottom once, the striker wasn’t stopped with his next effort, as he headed home from a CJ Hamilton cross.
Birmingham City loanee Emil Hansson had a couple of chances to extend the lead further, but was stopped by the Barrow keeper on both occasions.
Down the other end, Franco Ravizzoli was on hand to make a reaction save to deny Tyler Walker from close-range.
Ahead of the break, Zac Ashworth was lucky to remain on the pitch after appearing to bring down the Bluebirds forward on the edge of the box. The referee ultimately didn’t give a foul, and a decision concerning a card wasn’t required.
Shortly after the restart, the Seasiders claimed their third, with Andy Lyons flicking a Lee Evans corner past Winterbottom.
The fourth came courtesy of Dale Taylor off the bench. The striker found himself played through by fellow substitute Josh Bowler, as a lofted finish proved to be enough to find the back of the net.
Just before his withdrawal heading into the final 10 minutes, Banks added his second to ensure Bruce’s side went home with more goals than they’d scored in every other game combined this season.
Here’s how the Seasiders performed:
7. Scott Banks - 7
After a bright cameo against Northampton, Scott Banks quickly made an impression at Bloomfield Road with the opener. Photo: Gareth Evans
8. Jordan Brown - 7
Jordan Brown was the only player to remain in the starting XI from Saturday, and did a decent enough job in the centre of the park. Photo: Gareth Evans
9. Lee Evans - 6
Lee Evans was on hand with an assist for Andy Lyons' goal. Photo: Gareth Evans
10. Emil Hansson - 6
Emil Hansson was a lot more lively than his previous Blackpool outings, albeit against a League Two side. The winger had a couple of chances to score in the first half, but was denied by the Barrow keeper on both occasions. Photo: Gareth Evans
11. Tom Bloxham - 6
After missing out completely at the weekend, Tom Bloxham returned to the Seasiders' starting XI to play up front with Ashley Fletcher. The 21-year-old was able to produce some positive bursts in attack. Photo: Gareth Evans
12. Ashley Fletcher - 7
Ashley Fletcher did well in the build-up to Banks' opener before producing a strong header for his goal. Photo: Gareth Evans