The event is being held in a new £28m conference centre within the Winter Gardens on Friday, March 18, and Saturday, March 19.
The conference is estimated to be worth nearly £2.5m to the local economy, according to tourism bosses.
The last time a national party conference was held in Blackpool was in 2007 when the Conservatives gathered for their main October conference in the town.
Here’s a run down of who’s speaking and when ...
7. Nadhim Zahawi MP
Secretary of State for Education - Rt. Hon. Nadhim Zahawi MP will speak at 3.30pm Photo: WPA Pool
8. Michael Gove MP
Secretary of State for Levelling Up, Housing and Communities - Rt. Hon. Michael Gove MP will speak at 5.15pm Photo: Peter Byrne
9. George Eustice MP
Secretary of State for Environment, Food and Rural Affairs - Rt. Hon. George Eustice MP will open on Saturday at 10.15am Photo: Tolga Akmen
10. Priti Patel MP
The Home Secretary - Rt. Hon. Priti Patel MP takes the stage at 10.30am Photo: Ian Forsyth
11. Elizabeth Truss MP
The Foreign Secretary - Rt. Hon. Elizabeth Truss MP will speak at 10.45am on Saturday Photo: Leon Neal