LINE UPS: Pool remain unchanged for Orient clash
It means in-form striker Kyle Vassell continues his partnership with Jamille Matt up front as he looks to build on his good form, which has seen him net five times in his last three league games.
The back four remains as it has done for the majority of the season, with Kelvin Mellor, Tom Aldred, Clark Robertson and Andy Taylor playing in front of goalkeeper Sam Slocombe.
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Hide AdSkipper Danny Pugh is partnered in the middle of midfield by Jack Payne, with Brad Potts and Colin Daniel taking up the winger spots.
The Seasiders head into the match on good form after last weekend's 4-0 win at home to Notts County extended their unbeaten run to five games.
The O's, meanwhile, won 3-2 away at Colchester last time out but sit 19th in the League Two table.
Leyton Orient: Cisak, Hunt, Erichot, Parkes, Kennedy, Massey, Weir, Atangana, Collins, Simpson, Palmer
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Hide AdSubs: Sargeant, Pollock, Dunne, Ochieng, Semedo, Adeboyejo, McCallum
Blackpool: Slocombe, Mellor, Aldred, Robertson, Taylor, Daniel, Pugh, Payne, Potts, Vassell, Matt
Subs: Boney, Nolan, McAlister, Osayi-Samuel, Cullen, Philliskirk, Gnanduillet
Referee: Brendan Malone