LINE UPS: Blackpool make wholesale changes for Everton clash
Colin Daniel, Bright Osayi-Samuel, Mark Cullen and Armand Gnanduillet all come into the starting line-up.
Youngster Macauley Wilson is also in line to make his first professional start for the Seasiders. Meanwhile, Blackpool have only named four players on the substitute's bench.
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Hide AdEverton U21 manager David Unsworth has named senior player Darron Gibson among his youthful starting eleven.
With all four sides in the group level on three points, the winners of tonight's game will make it through to the next round.
Everton U21: Hewelt, Jones, Browning, Yarney, Foulds, Robinson, Baningime, Gibson, Charsley, Henen, Dyson.
Subs: Renshaw, Duffus, Evans, Holland, Brewster, Bainbridge, Kiersey.
Blackpool: Slocombe, Wilson, Aimson, Nolan, Daniel, Osayi-Samuel, McAlister, Cain, Yeates, Cullen, Gnanduillet.
Subs: Boney, Higham, Payne, Philliskirk.
Referee: Chris Kavanagh