A contraflow has been put in place outside the Cuadrilla fracking site this morning following a lock-on protest, say police.
Four campaigners are believed to be staging a lock-on in the carriageway on Preston New Road.
Traffic is reported to be "heavy".
A police spokesman said: "Please be aware of four campaigners locked on in both sides of the carrigeway between the fracking site and Westby Road.
"This has caused us to have to manage single flow of traffic. Traffic can still pass between the two lock-ons but please drive past slowly and with care especially in the current weather conditions.
"While we will endeavour to keep the carrigeway open and flowing, the safety of everyone is paramount. This delay is in addition to the traffic light contraflow near Whitehills."
Drivers are advised to expect disruption and seek an alternative route if possible.