Gary Bowyer has opted to go with the same side that defeated Yeovil 3-0 last week for today's clash at Colchester.
The Tangerines were in fine form last week and will be hoping for a similar performance as they make another long trip to Essex.
Striker Danny Philliskirk returns from injury but has to settle for a place on the bench, where he is joined by youngster Bright Osayi-Samuel.
Fellow striker Jamille Matt is still not fit enough to make the squad, having only returned to training on Friday.
This is how the two sides will line up:
Colchester: Walker, Brindley, Prosser, Eastman, Kinsella; Wright, Lapslie, Guthrie, Dickenson, Szmodics, Porter
Subs: Bransgrove, Vincent-Young, Wynter, Slater, Kamara, Fosu, Johnstone
Blackpool: Slocombe, Mellor, Aldred, Robertson, Taylor, Daniel, Pugh, McAlister, Potts, Gnanduillet, Vassell
Subs: Lyness, Aimson, Cain, Payne, Yeates, Osayi-Samuel, Philliskirk
Referee: Brendan Malone