A man needed emergency surgery after being stabbed following an argument at a South Shore flat.
Detectives are investigating the attack, which is alleged to have taken place at an address on St Heliers Road on Wednesday evening.
It is the second stabbing in South Shore in just two days after a man was seen bleeding in the street following an attack at a property on Lindale Gardens the day before.
Police were called to St Heliers Road at around 7pm on Wednesday, where there was a reported disturbance.
It is thought a verbal argument escalated and a scuffle broke out, during which the 30-year-old victim, who is local to the area, received stab wounds.
A 29-year-old man was yesterday being quizzed by detectives after handing himself in to police.
Det Sgt Stuart Reid, of Blackpool CID, said: “The victim had serious injuries and had surgery on Wednesday night.
“He is in Blackpool Victoria Hospital where he is in a stable condition.
“It would appear there was a verbal argument and the two men have come to blows.
“There was a scuffle during which one man has stabbed the other.
“Inquiries are ongoing and we are carrying out searches to recover the weapon.”
He said a 29-year-old man from Blackpool had been arrested on suspicion of causing grievous bodily harm and was being questioned by police.
Det Sgt Reid added: “We are not asking for any further witnesses or searching for anyone else in relation to this offence.”
On Tuesday, a 22-year-old man was rushed to hospital after being stabbed at a property on Lindale Gardens.
The victim suffered heavy blood loss but later discharged himself from hospital.
Three people were arrested and released on police bail following the attack.
The cases are not linked.