Demonstrators from the Fylde coast joined anti-fracking activists from across the UK at a protest to halt work at a drilling site in Salford.
Energy company IGas has permission to start drilling to see what type of gas or oil can be found at Barton Moss.
Protesters tried to stop lorries carrying drilling equipment from entering the site.
Bob Dennett, from Residents Action On Fylde Fracking, who was at the site earlier this week, said: “People are determined to continue protesting against drilling until the Government sees how dangerous it is.
“We will carry on until they get the message.
“When I was at the protest, the atmosphere was lively and jovial so I was shocked to see people being arrested by the police.”
A spokesperson from IGas said: “We respect the right to peaceful protest.
“However we do not condone any activity that is illegal or disrupts the local residents or local businesses and we are saddened by this sort of action today.
“We are working with the relevant authorities to minimise the disruption to local residents and business and continue to operate in accordance with all the necessary regulation and permitting.”
Around four arrests are believed to have been made with at least 40 police officers deployed.